CMS is soliciting nominations for a total of 42 voting and nonvoting members of the Medicare Evidence Development & Coverage Advisory Committee (MedCAC), which advises CMS on the adequacy of scientific evidence available to CMS for Medicare “reasonable and necessary” determinations. Nominations must be received by September 24, 2012. CMS also is seeking nominations for two new members to the Advisory Panel on Hospital Outpatient Payment (HOP), which advises the agency on the clinical integrity of the Ambulatory Payment Classification (APC) groups and their associated weights, and supervision of hospital outpatient services. Nominations are due by October 23, 2012.