CMS has posted the October 2012 update to Medicare Part B average sales price (ASP) files, which will be used to pay for Part B covered drugs for the fourth quarter of 2012. CMS reports that drug prices in the market remain relatively stable, with average prices for the top Part B drugs decreasing by 1.7% in the fourth quarter of 2012 compared to the previous quarter. CMS also notes that it is continuing to delay implementation of average manufacturer price (AMP)-based price substitution policy at this time for “a variety of operational issues.”