The Agency for Healthcare Research and Quality (AHRQ) Effective Health Care Program is sponsoring a symposium/webcast on original research methods for comparative effectiveness (CER) and patient-centered outcomes research (PCOR) in Rockville, Maryland on June 12 and 13, 2012. AHRQ is inviting the submission of papers, presentations, and abstracts for the symposium, titled “From Efficacy to Effectiveness.”