The National Cancer Institute (NCI) has published a request for information (RFI) as part of a consumer health initiative to develop collaborations that produce evidence-based informatics resources that will aid providers in clinical settings and promote positive health behaviors among consumers. NCI is soliciting ongoing information from commercial information technology, government, health care, education, research, and advocacy organizations on the state of informatics for consumer health. Information of interest includes journal articles, funding opportunities, and product development plans that can be shared publicly on a consumer health-related web site. Content areas may include care coordination, eHealth tools and strategies, early prevention and detection, electronic health records, clinical decision support, health care disparities, and telehealth/telemedicine. Comments should be submitted by February 1, 2011.